If anyone with a Quadro has issues, try updating your graphics card drivers
I used to have loads of problems with games before I updated my Quadro drivers. As in, half the games I owned would crash on start or randomly die while I was playing it. Since the driver update, I don't have any issues
Some Quadro cards (my one for instance) don't have any recent drivers listed as compatible. I just downloaded one of the newer ones that listed other Quadro's of a similar age to mine and the drivers installed and worked, and they resolved all my problems!
Before that I tried the newest driver that did mention my graphics card, that fixed most of the games, but not all.
Recettear runs at a solid 60 fps all the time, all settings on max, on my Core 2 Duo / Quadro. The Quadro cards are functionally identical to the GeForces, in some cases the only difference is 1 extra resistor on the Quadro. They aren't "crappy for gaming" if you make sure you pick good drivers.
Incidentally, the Game Over screen seems to have a mildly annoying flickery effect - I think its intentional, but its a bit fast